The Nerve Centre is a renowned arts and nightclub venue located in Derry, Northern Ireland. Established in 1990, it originally started as a ground-breaking initiative to promote creative and cultural development among the youth of the area. Over the years, The Nerve Centre evolved into one of Ireland's most influential cultural hubs, combining live music, arts training, film production, and digital media.

Its reputation is anchored both in its innovative spirit and its role as a vital safe space for artistic expression, especially during the post-Troubles era when Derry sought to redefine itself as a city of culture and creativity. The venue quickly built a name far beyond the local scene, drawing acts from across Ireland, the UK, and internationally, while fostering the city’s own musical and artistic talent through workshops, mentoring, and outreach programs. In the early 2000s, The Nerve Centre relocated from its original site on Strand Road to a purpose-built facility in Magazine Street, enhancing its infrastructure and expanding its activities to include rehearsal studios, recording facilities, and multimedia labs.

This move solidified its position at the heart of Derry’s increasingly vibrant cultural quarter. Beyond club nights and concerts, The Nerve Centre has been central in organizing key community events, educational initiatives, and creative festivals, including its major role in Derry’s City of Culture celebrations in 2013. Its ongoing commitment to youth and popular culture, as well as its influential film and animation production work, have marked it as a cornerstone of the region’s artistic and social life.

Notable artists who have performed at The Nerve Centre include international acts such as Snow Patrol, Therapy?, Ash, The Undertones, and The Divine Comedy, along with local talents like SOAK, Wood Burning Savages, and Paddy Nash & The Happy Enchiladas. The venue has also hosted club nights featuring prominent DJs from the UK and Ireland, and it continues to be a launchpad for many up-and-coming artists in the region.